Endocrine Abstracts

Renal transplantation is the optimal treatment strategy for patients with end-stage renal disease (ESRD); few are afforded the opportunity due to limited organ supply. Of the alternatives, peritoneal dialysis (PD) and hemodialysis (HD), it is unclear which confers the greater survival advantage, as prior comparisons have demonstrated conflicting results due to lack of case-mix adjustment, limited follow-up, and failure to consider switches in modality over time.<p class="a...

Prior studies have demonstrated that diabetes as a cause of or contributing factor to end stage renal disease (ESRD) has a detrimental impact on survival. What is unclear is whether this effect varies by age and gender.Methods: The objective of this study was to evaluate mortality differences by age and gender among diabetic and non-diabetic ESRD patients in a national cohort. Data on all new ESRD patients (n=451,296) who were initiated on dialysi...

Apolipoprotein (Apo)-B is a strong predictor of coronary risk in the general population. Whether it contributes to coronary disease in patients with reduced kidney function is unclear. We examined the prevalence and relationship of Apo-B with physician-diagnosed myocardial infarction among 7,404 adults age >20 years with reduced glomerular filtration rate (GFR) in the U.S. population. GFR was estimated Modification of Diet in Renal Disease Study (MDRD) equation and calibra...

A Multicystic dysplastic kidney (MCDK) is a congenital, renal, cystic transformation usually diagnosed perinatally with 1:1000-4,000 incidence1. The natural history of MCDK is disputed with involution1, enlargement and development of hypertension2, infection and malignant transformation reported in the literature. We describe the incidental detection of An occult MCDK was detected in a 25-year-old chef who presented with a 4 month history of di...

A Multicystic Dysplastic Kidney (MCDK) is a congenital, renal, cystic transformation usually diagnosed perinatally with 1:1000 to 4,000 incidence1. The natural history of MCDK is disputed with involution1, enlargement and development of hypertension2, infection and malignant transformation reported in the literature. We describe the case of a 25-year-old chef in whom an occult MCDK was incidentally detected. He presented with a four month histo...